Impaired executive function in male MDMA (?ecstasy?) users
نویسندگان
چکیده
منابع مشابه
Executive function in abstinent MDMA ('ecstasy') users.
BACKGROUND Methylenedioxymethamphetamine (MDMA, or 'Ecstasy') is a growingly popular recreational drug of abuse that is known to damage brain serotonergic neurons in animals and possibly humans. Few functional consequences of MDMA-induced serotonin neurotoxicity have been identified, either in animals or humans. This study sought to determine whether individuals with a history of MDMA use showe...
متن کاملSyllogistic reasoning performance in MDMA (Ecstasy) users.
Previous research has demonstrated working memory and executive deficits in recreational users of MDMA (3,4-methylenedioxymethamphetamine; Ecstasy). In turn, both of these constructs have been implicated in syllogistic reasoning performance. Twenty-two MDMA users (mean age = 21.36) and 26 MDMA nonuser controls (mean age = 21.31) were tested on syllogisms of varying difficulty and on measures of...
متن کاملEvidence for selective executive function deficits in ecstasy/polydrug users.
Previous research has suggested that the separate aspects of executive functioning are differentially affected by ecstasy use. Although the inhibition process appears to be unaffected by ecstasy use, it is unclear whether this is true of heavy users under conditions of high demand. Tasks loading on the updating process have been shown to be adversely affected by ecstasy use. However, it remains...
متن کاملExecutive working memory deficits in abstinent ecstasy/MDMA users: a critical review.
AIMS This review examined studies of executive functioning in abstinent ecstasy (3,4-methylenedioxymethamphetamine, MDMA) users on tasks which had been empirically mapped onto updating, shifting, inhibition and accessing long-term memory executive processes. Studies of some aspects of visuospatial memory performance were also included because of the investment of executive resources in such tas...
متن کاملImpaired cognitive performance in drug free users of recreational ecstasy (MDMA)
Objectives—Ecstasy (3,4-methylenedioxymethamphetamine (MDMA) and related congerers: MDA, MDEA) is the name given to a group of popular recreational drugs. Animal data raise concern about neurotoxic eVects of high doses of ecstasy on central serotonergic systems. The threshold dose for neurotoxicity in humans is not clear and serotonin is involved in several functions including cognition. The pu...
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ژورنال
عنوان ژورنال: Psychopharmacology
سال: 2004
ISSN: 0033-3158,1432-2072
DOI: 10.1007/s00213-004-1832-8